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1243-33-0

1243-33-0结构式

常用中文名：美非氯嗪
常用英文名：Mefeclorazine
CAS号：1243-33-0
分子式：C₂₀H₂₅ClN₂O₂
分子量：360.87800
发布时间：2018-04-28 08:00:00
更新时间：2024-07-19 12:07:08

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中文名	美非氯嗪
英文名	1-(2-chlorophenyl)-4-[2-(3,4-dimethoxyphenyl)ethyl]piperazine
英文别名	1-(2-chloro-phenyl)-4-(3,4-dimethoxy-phenethyl)-piperazine Mefeclorazina [INN-Spanish] 4-<2-Chlor-phenyl>-1-<3,4-dimethoxy-phenethyl>-piperazin 1-o-Chlorophenyl-4-(3,4-dimethoxyphenethyl)piperazine Mefeclorazinum [INN-Latin] 1-(2-Chlorphenyl)-4-(3,4-dimethoxyphenethyl)piperazine N-(Dimethoxy-3,4-phenethyl),-N'-(chloro-2-phenyl) piperazine Piperazine,1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl) Mefeclorazine SD 218-06 Mepheclorazin

密度	1.16g/cm3
沸点	490.1ºC at 760 mmHg
分子式	C₂₀H₂₅ClN₂O₂
分子量	360.87800
闪点	250.2ºC
精确质量	360.16000
PSA	24.94000
LogP	3.72480
蒸汽压	9.43E-10mmHg at 25°C
折射率	1.57

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL2803000

CHEMICAL NAME :: Piperazine, 1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl)-

CAS REGISTRY NUMBER :: 1243-33-0

BEILSTEIN REFERENCE NO. :: 0627902

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H25-Cl-N2-O2

MOLECULAR WEIGHT :: 360.92

WISWESSER LINE NOTATION :: T6N DNTJ A2R CO1 DO1& DR CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - central sympatholytic Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - bronchiolar dilation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,104,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 133,29,1961

海关编码	2933599090

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%