4755-59-3

• 常用中文名：5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
• 常用英文名：5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
• CAS号：4755-59-3
• 分子式：C₁₈H₂₀ClN₃O
• 分子量：329.82400
• 发布时间：2016-01-07 04:31:14
• 更新时间：2024-01-07 17:18:46

名称

• 英文名: 5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
• 英文别名: Clodazone; Clodazone [INN-French]; 5-chloro-1-(3-dimethylamino-propyl)-3-phenyl-1,3-dihydro-benzoimidazol-2-one; Clodazon [INN]; CLODAZON; 2-Benzimidazolinone,5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl; Clodazona [INN-Spanish]; 5-Chloro-1-(3-(dimethylamino)propyl)-3-phenyl-2-benzimidazolinone; Clodazonum [INN-Latin]

物化性质

• 密度: 1.232g/cm3
• 沸点: 466.3ºC at 760mmHg
• 分子式: C₁₈H₂₀ClN₃O
• 分子量: 329.82400
• 闪点: 235.8ºC
• 精确质量: 329.12900
• PSA: 30.17000
• LogP: 3.39730
• 折射率: 1.609

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE1800000 CHEMICAL NAME : 2-Benzimidazolinone, 5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl- CAS REGISTRY NUMBER : 4755-59-3 BEILSTEIN REFERENCE NO. : 0894387 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C18-H20-Cl-N3-O MOLECULAR WEIGHT : 329.86 WISWESSER LINE NOTATION : T6MTJ DXQR&R HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 142 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 77 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 715 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 505 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968