4755-59-3

4755-59-3 structure

4755-59-3 structure

Name: 5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
Chemical Name: 5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
CAS Number: 4755-59-3
Molecular Formula: C₁₈H₂₀ClN₃O
Molecular Weight: 329.82400
Create Date: 2016-01-07 04:31:14
Modify Date: 2024-01-07 17:18:46

Name	5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
Synonyms	Clodazone Clodazone [INN-French] 5-chloro-1-(3-dimethylamino-propyl)-3-phenyl-1,3-dihydro-benzoimidazol-2-one Clodazon [INN] CLODAZON 2-Benzimidazolinone,5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl Clodazona [INN-Spanish] 5-Chloro-1-(3-(dimethylamino)propyl)-3-phenyl-2-benzimidazolinone Clodazonum [INN-Latin]

Density	1.232g/cm3
Boiling Point	466.3ºC at 760mmHg
Molecular Formula	C₁₈H₂₀ClN₃O
Molecular Weight	329.82400
Flash Point	235.8ºC
Exact Mass	329.12900
PSA	30.17000
LogP	3.39730
Index of Refraction	1.609

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE1800000

CHEMICAL NAME :: 2-Benzimidazolinone, 5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl-

CAS REGISTRY NUMBER :: 4755-59-3

BEILSTEIN REFERENCE NO. :: 0894387

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C18-H20-Cl-N3-O

MOLECULAR WEIGHT :: 329.86

WISWESSER LINE NOTATION :: T6MTJ DXQR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 142 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 77 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 715 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 505 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968