10169-34-3

• 常用中文名：Mitomycin D
• 常用英文名：Mitomycin D
• CAS号：10169-34-3
• 分子式：C₁₅H₁₈N₄O₅
• 分子量：334.32700
• 发布时间：2016-02-25 14:09:20
• 更新时间：2024-01-10 11:19:15

名称

• 英文名: Mitomycin D
• 英文别名: (1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione

物化性质

• 密度: 1.64g/cm3
• 沸点: 601.7ºC at 760mmHg
• 分子式: C₁₅H₁₈N₄O₅
• 分子量: 334.32700
• 闪点: 317.7ºC
• 精确质量: 334.12800
• PSA: 138.96000
• 蒸汽压: 5.47E-17mmHg at 25°C
• 折射率: 1.723

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CN0726000 CAS REGISTRY NUMBER : 10169-34-3 LAST UPDATED : 199706 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C15-H18-N4-O5 MOLECULAR WEIGHT : 334.37 WISWESSER LINE NOTATION : T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KZ L1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 430 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 36,1461,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 20,72,1967

合成路线

78879-23-9 ~% 10169-34-3

文献：Journal of Organic Chemistry, , vol. 54, # 25 p. 5908 - 5911

105616-80-6 ~67% 10169-34-3

文献：Journal of Organic Chemistry, , vol. 54, # 25 p. 5908 - 5911

4055-40-7 ~% 10169-34-3

文献：Journal of Organic Chemistry, , vol. 57, # 6 p. 1799 - 1807

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4055-40-7 78879-23-9
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