485-34-7

• 常用中文名：Ethyl 6-methyl-2-phenyl-4-quinolinecarboxylate
• 常用英文名：Ethyl 6-methyl-2-phenyl-4-quinolinecarboxylate
• CAS号：485-34-7
• 分子式：C₁₉H₁₇NO₂
• 分子量：291.34400
• 发布时间：2017-04-19 23:55:01
• 更新时间：2024-01-10 14:15:39

名称

• 英文名: ethyl 6-methyl-2-phenylquinoline-4-carboxylate
• 英文别名: Neocinchophen; Neophan; Tolysin; 6-methyl-2-phenyl-quinoline-4-carboxylic acid ethyl ester; Neoatophan; Neoquinophan; 6-Methyl-2-phenyl-chinolin-4-carbonsaeure-aethylester; Neocincophen; Novo-rheumatophin; Novatophan; Neomagnephen; Neu-nylofanol

物化性质

• 密度: 1.152g/cm3
• 沸点: 455.7ºC at 760 mmHg
• 分子式: C₁₉H₁₇NO₂
• 分子量: 291.34400
• 闪点: 229.4ºC
• 精确质量: 291.12600
• PSA: 39.19000
• LogP: 4.38690
• 蒸汽压: 1.72E-08mmHg at 25°C
• 折射率: 1.613

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VB2251850 CHEMICAL NAME : 4-Quinolinecarboxylic acid, 6-methyl-2-phenyl-, ethyl ester CAS REGISTRY NUMBER : 485-34-7 BEILSTEIN REFERENCE NO. : 0251071 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H17-N-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7 gm/kg/7D-I TOXIC EFFECTS : Liver - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 48,341,1933 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 21600 mg/kg/7W-I TOXIC EFFECTS : Liver - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 48,341,1933

合成路线

64-17-5 174636-75-0 ~10% 485-34-7

文献：Boa, Andrew N.; Canavan, Shane P.; Hirst, Paul R.; Ramsey, Christopher; Stead, Andrew M.W.; McConkey, Glenn A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 6 p. 1945 - 1967

98-86-2 ~% 485-34-7

文献：Boa, Andrew N.; Canavan, Shane P.; Hirst, Paul R.; Ramsey, Christopher; Stead, Andrew M.W.; McConkey, Glenn A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 6 p. 1945 - 1967

74-96-4 ~% 485-34-7

文献：Chem. Fabr. Schering Patent: DE275963 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 973

75-00-3 ~% 485-34-7

文献：Chem. Fabr. Schering Patent: DE275963 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 973

7664-93-9 60538-98-9 ~% 485-34-7

文献：Buchman; Howton Journal of the American Chemical Society, 1946 , vol. 68, p. 2718

60538-98-9 ~% 485-34-7

文献：Boa, Andrew N.; Canavan, Shane P.; Hirst, Paul R.; Ramsey, Christopher; Stead, Andrew M.W.; McConkey, Glenn A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 6 p. 1945 - 1967

7647-01-0 60538-98-9 ~% 485-34-7

文献：Kaku Yakugaku Zasshi, 1930 , vol. 50, p. 235,238; dtsch. Ref. S. 31 Chem.Abstr., 1930 , p. 3511 Full Text Show Details Fourneau et al. Ann. Inst. Pasteur, 1930 , vol. 44, p. 719,729

上下游产品

上游产品  8
64-17-5 174636-75-0 98-86-2 74-96-4
75-00-3 7664-93-9 60538-98-9 7647-01-0
下游产品  1
41874-25-3