170851-70-4

• 常用中文名：伊帕瑞林
• 常用英文名：Ipamorelin
• CAS号：170851-70-4
• 分子式：C₃₈H₄₉N₉O₅
• 分子量：711.853
• 发布时间：2018-04-03 08:00:00
• 更新时间：2024-01-07 19:46:07
• Ipamorelin, also known as NNC-26-0161, is a a ghrelin mimetic. Ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats. Ipamorelin may ameliorate the symptoms in patients with POI. Ipamorelin accelerates gastric emptying in a rodent model of postoperative ileus through the stimulation of gastric contractility by activating a ghrelin receptor-mediated mechanism involving cholinergic excitatory neurons.

名称

• 中文名: 依帕瑞林
• 英文名: (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(4H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
• 中文别名: 伊莫瑞林; 醋酸伊帕瑞林; 伊帕瑞林
• 英文别名: L-Lysinamide, 2-methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-; UNII-Y9M3S784Z6; Y9M3S784Z6; 2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide; Ipamorelin; 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide.; 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 1185.5±65.0 °C at 760 mmHg
• 分子式: C₃₈H₄₉N₉O₅
• 分子量: 711.853
• 闪点: 670.7±34.3 °C
• 精确质量: 711.385681
• PSA: 240.21000
• LogP: 1.72
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.624
• 储存条件: 2-8°C，密闭，干燥