5544-25-2

• 常用中文名：ANTHRAMYCIN METHYL ETHER
• 常用英文名：ANTHRAMYCIN METHYL ETHER
• CAS号：5544-25-2
• 分子式：C₁₇H₁₉N₃O₄
• 分子量：329.35000
• 发布时间：2017-12-25 07:12:59
• 更新时间：2024-04-02 13:14:22

名称

• 英文名: (E)-3-[(6R,6aS)-4-hydroxy-6-methoxy-3-methyl-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]prop-2-enamide
• 英文别名: Roche 5-9000; Anthramycin-methylether; Antibiotic A; Anthramycin 11-methyl ether; 11-O-Methyl-anthramycin

物化性质

• 密度: 1.4g/cm3
• 沸点: 631.8ºC at 760 mmHg
• 分子式: C₁₇H₁₉N₃O₄
• 分子量: 329.35000
• 闪点: 335.9ºC
• 精确质量: 329.13800
• PSA: 104.89000
• LogP: 2.01470
• 折射率: 1.672

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UY8429500 CHEMICAL NAME : 1H-Pyrrolo(2,1-c)(1,4)benzodiazepine-2-acrylamide, 5,10,11,11a-tetrahydro-9-hydroxy- 11-methoxy-8-methyl-5-oxo-, (E)-, monohydrate CAS REGISTRY NUMBER : 5544-25-2 LAST UPDATED : 199306 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C17-H19-N3-O4.H2-O MOLECULAR WEIGHT : 347.41 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3400 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 730 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2900 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : Mutation test systems - not otherwise specified TYPE OF TEST : DNA inhibition MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Ascites tumor DOSE/DURATION : 5 umol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,2195,1969

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