875318-46-0

• 常用中文名：2-(4-羟甲基哌啶-1-基)嘧啶-5-甲酸乙酯
• 常用英文名：Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate
• CAS号：875318-46-0
• 分子式：C₁₃H₁₉N₃O₃
• 分子量：265.30800
• 发布时间：2016-12-15 13:56:44
• 更新时间：2024-01-14 17:38:29

名称

• 中文名: 2-(4-羟甲基哌啶-1-基)嘧啶-5-甲酸乙酯
• 英文名: ethyl 2-[4-(hydroxymethyl)-1-piperidyl]pyrimidine-5-carboxylate
• 英文别名: (2S,3R)-2-Dimethylamino-3-methyl-N-[(3R,4S,7S)-7-(2-methylpropyl)-5,8-dioxo-3-phenyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14(1),15-tetren-4-yl]pentanamide; N-methyl-nummularine-D; Integerrenine; intermediate 7; intermediate 3; Integerrenin; N,N-dimethyl-L-isoleucine (4S)-7t-isobutyl-5,8-dioxo-3t-phenyl-2-oxa-6,9-diaza-1(1,4)-benzena-cycloundecaphan-10c-en-4r-ylamide

物化性质

• 沸点: 447.7°C at 760 mmHg
• 分子式: C₁₃H₁₉N₃O₃
• 分子量: 265.30800
• 闪点: 224.6±0.0 °C
• 精确质量: 265.14300
• PSA: 75.55000
• LogP: 0.92700
• 储存条件: 室温，干燥密封

合成路线

6457-49-4 148550-51-0 ~99% 875318-46-0

文献：CHROMA THERAPEUTICS LTD. Patent: WO2008/53131 A1, 2008 ; Location in patent: Page/Page column 51; 53 ; WO 2008/053131 A1

6457-49-4 89793-12-4 ~95% 875318-46-0

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ; Location in patent: Page/Page column 70 ;

33458-27-4 ~% 875318-46-0

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

763-69-9 ~% 875318-46-0

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

95928-49-7 ~% 875318-46-0

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

879008-23-8 ~% 875318-46-0

文献：CURIS, INC. Patent: WO2009/36016 A1, 2009 ;

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