41716-84-1

• 常用中文名：Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride
• 常用英文名：Piperazine,1-(2-benzofuranylcarbonyl)-4- (phenylmethyl)-,monohydrochloride
• CAS号：41716-84-1
• 分子式：C₂₀H₂₁ClN₂O₂
• 分子量：356.84600
• 发布时间：2017-02-24 23:57:08
• 更新时间：2024-02-03 17:58:05

名称

• 英文名: 1-benzofuran-2-yl-(4-benzylpiperazin-1-yl)methanone,hydrochloride
• 英文别名: Befuraline HCl; Befuraline hydrochloride; DIV 154

物化性质

• 沸点: 477.5ºC at 760 mmHg
• 分子式: C₂₀H₂₁ClN₂O₂
• 分子量: 356.84600
• 闪点: 242.6ºC
• 精确质量: 356.12900
• PSA: 36.69000
• LogP: 4.06860

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TK8220500 CHEMICAL NAME : Piperazine, 1-(2-benzofuranylcarbonyl)-4-(phenylmethyl)-, monohydrochloride CAS REGISTRY NUMBER : 41716-84-1 LAST UPDATED : 198812 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H20-N2-O2.Cl-H MOLECULAR WEIGHT : 356.88 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2530 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 720 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 32200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 48500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,193,1979