910297-62-0

• 常用中文名：达沙替尼羧酸乙酯
• 常用英文名：Dasatinib Carboxylic Acid Ethyl Ester
• CAS号：910297-62-0
• 分子式：C₂₄H₂₈ClN₇O₃S
• 分子量：530.04200
• 发布时间：2018-10-17 14:04:46
• 更新时间：2024-01-13 12:38:11

名称

• 中文名: 达沙替尼羧酸乙酯
• 英文名: ethyl 2-[4-[6-[[5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl]amino]-2-methylpyrimidin-4-yl]piperazin-1-yl]acetate
• 英文别名: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid Ethyl Ester; ethyl 2-(4-(6-(5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-ylamino)-2-methylpyrimidin-4-yl)piperazin-1-yl)acetate; Dasatinib Carboxylic Acid Ethyl Ester; Dasatinib Impurity 2

物化性质

• 分子式: C₂₄H₂₈ClN₇O₃S
• 分子量: 530.04200
• 精确质量: 529.16600
• PSA: 144.31000
• LogP: 4.34420

合成路线

910297-51-7 105-36-2 ~89% 910297-62-0

文献：CURIS, INC. Patent: WO2008/33746 A2, 2008 ; Location in patent: Page/Page column 58 ; WO 2008/033746 A2

40004-08-8 302964-08-5 ~89% 910297-62-0

文献：Bristol-Myers Squibb Company Patent: US2007/219370 A1, 2007 ; Location in patent: Page/Page column 29 ;