13551-92-3

• 常用中文名：3-(2-硝基-1H-咪唑-1-基)-1,2-丙二醇
• 常用英文名：1,2-Propanediol,3-(2-nitro-1H-imidazol-1-yl)-
• CAS号：13551-92-3
• 分子式：C₆H₉N₃O₄
• 分子量：187.15300
• 发布时间：2019-02-05 13:19:16
• 更新时间：2024-03-05 13:11:08

名称

• 中文名: 3-(2-硝基-1H-咪唑-1-基)-1,2-丙二醇
• 英文名: 3-(2-nitroimidazol-1-yl)propane-1,2-diol
• 英文别名: 2-Hydroxy-3-(2-nitro-1-imidazolyl)-propanol; Desmethylmisonidazole; EINECS 236-932-1; 3-(2-Nitro-1H-imidazol-1-yl)propane-1,2-diol; 1-(2-nitro-1-imidazolyl)-3-hydroxypropanol; Ro 5-9963; O-Desmethyl-misonidazole; 3-(2-nitro-imidazol-1-yl)-propane-1,2-diol; 3-(2-Nitro-I-imidazolyl)-1,2-propanediol; 1-(2,3-dihydroxypropyl)-2-nitroimidazole; Demethylmisonidazole

物化性质

• 密度: 1.61g/cm3
• 沸点: 521.5ºC at 760mmHg
• 分子式: C₆H₉N₃O₄
• 分子量: 187.15300
• 闪点: 269.2ºC
• 精确质量: 187.05900
• PSA: 104.10000
• 蒸汽压: 1.05E-11mmHg at 25°C
• 折射率: 1.643

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TZ0818000 CHEMICAL NAME : 1,2-Propanediol, 3-(2-nitroimidazol-1-yl)- CAS REGISTRY NUMBER : 13551-92-3 BEILSTEIN REFERENCE NO. : 0613156 LAST UPDATED : 199612 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C6-H9-N3-O4 MOLECULAR WEIGHT : 187.18 WISWESSER LINE NOTATION : T5N CNJ A1YQ1Q BNW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5076 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2532 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - contraction (isolated tissue) TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2730 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1800 mg/kg TOXIC EFFECTS : Behavioral - food intake (animal) Gastrointestinal - nausea or vomiting TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9020 mg/kg/20D-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 3340 mg/kg/20D-I TOXIC EFFECTS : Behavioral - ataxia Blood - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 2250 mg/kg/20D-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain MUTATION DATA TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - mouse Embryo DOSE/DURATION : 1 mmol/L/3D (Continuous) REFERENCE : 45OJAG "Radiation Sensitizers: Their Use in the Clinical Management of Cancer, Proceedings of the Conference, Key Biscayne, FL, 1979," Brady, L.W., ed., New York, Masson Pub. USA, Inc., 1980 Volume(issue)/page/year: -,146,1980

安全

• 海关编码: 2933290090

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海关

海关编码	2933290090
中文概述	2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%