443-33-4
443-33-4结构式
- 常用中文名：2-氯-6-氟苯甲醛肟
- 常用英文名：2-CHLORO-6-FLUOROBENZALDOXIME
- CAS号：443-33-4
- 分子式：C7H5ClFNO
- 分子量：173.57200
- 相关类别： 有机原料 有机氟化合物 氟苯甲醛系列
- 发布时间：2018-10-04 08:22:24
- 更新时间：2024-01-03 16:27:45
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主要用作医药抗生素和农药植物生长调节剂等原料合成的原料。
| 中文名 | 2-氯-6-氟苯甲醛肟 |
|---|---|
| 英文名 | 2-chloro-6-fluorobenzaldoxime |
| 英文别名 |
MFCD00837704
(NE)-N-[(2-chloro-6-fluorophenyl)methylidene]hydroxylamine EINECS 207-135-6 2-Chloro-6-fluorobenzaldehyde oxime 2-Chloro-6-fluorobenzaldoxime |
| 密度 | 1.32 g/cm3 |
|---|---|
| 沸点 | 238ºC at 760 mmHg |
| 熔点 | 129-133 °C(lit.) |
| 分子式 | C7H5ClFNO |
| 分子量 | 173.57200 |
| 闪点 | 97.8ºC |
| 精确质量 | 173.00400 |
| PSA | 32.59000 |
| LogP | 2.28720 |
| 蒸汽压 | 0.0237mmHg at 25°C |
| 折射率 | 1.533 |
| 分子结构 | 1、 摩尔折射率：40.63 2、 摩尔体积（m3/mol）：130.8 3、 等张比容（90.2K）：324.2 4、 表面张力（dyne/cm）：37.7 5、 极化率（10 -24cm 3）：16.10 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:2.4 2.氢键供体数量:1 3.氢键受体数量:3 4.可旋转化学键数量:1 5.互变异构体数量:2 6.拓扑分子极性表面积32.6 7.重原子数量:11 8.表面电荷:0 9.复杂度:153 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:1 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 一、物性数据 性状：白色至微黄色液体 密度（g/mL,25/4℃）：不可用 相对蒸汽密度（g/mL,空气=1）：不可用 熔点（ºC）：不可用 沸点（ºC,常压）：118-120 沸点（ºC,5.2kPa）：不可用 折射率：不可用 闪点（ºC）：不可用 比旋光度（º）：不可用 自燃点或引燃温度（ºC）：不可用 蒸气压（kPa,25ºC）：不可用 饱和蒸气压（kPa,60ºC）：不可用 燃烧热（KJ/mol）：不可用 临界温度（ºC）：不可用 临界压力（KPa）：不可用 油水（辛醇/水）分配系数的对数值：不可用 爆炸上限（%,V/V）：不可用 爆炸下限（%,V/V）：不可用 溶解性：不可用 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 443-33-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: light yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 133 - 134 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H5ClFNO Molecular Weight: 174 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 443-33-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Chloro-6-fluorobenzaldehyde oxime - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 443-33-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 443-33-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 443-33-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
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毒理学数据: 二、毒理学数据： 急性毒性：不可用。 生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。
|
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H302-H319 |
| 警示性声明 | P305 + P351 + P338 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) | Xi:Irritant; |
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | S26-S26,37/39 |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 2 |
| 海关编码 | 2928000090 |
|
~95%
443-33-4 |
| 文献：Hajipour, Abdol Reza; Mallakpour, Shadpour E.; Imanzadeh, Gholamhasan Journal of Chemical Research - Part S, 1999 , # 3 p. 228 - 229 |
|
~%
443-33-4 |
| 文献：Lock Chemische Berichte, 1936 , vol. 69, p. 2253,2255 |
| 上游产品 2 | |
|---|---|
| 下游产品 7 | |
| 海关编码 | 2928000090 |
|---|---|
| 中文概述 | 2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |