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6268-03-7

6268-03-7结构式
6268-03-7结构式

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英文名 1,2-bis(2-methoxyphenyl)guanidine
英文别名 Di-o-anisylguanidine
N,N'-di-o-anisole guanidine
密度 1.15g/cm3
沸点 447.1ºC at 760 mmHg
分子式 C15H17N3O2
分子量 271.31400
闪点 224.2ºC
精确质量 271.13200
PSA 66.37000
LogP 3.40830
折射率 1.57

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ME8656000
CHEMICAL NAME :
Guanidine, N,N'-bis(2-methoxyphenyl)-
CAS REGISTRY NUMBER :
6268-03-7
BEILSTEIN REFERENCE NO. :
3387288
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H17-N3-O2
MOLECULAR WEIGHT :
271.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Endocrine - hyperglycemia
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 41,127,1931
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Endocrine - hyperglycemia
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 41,127,1931

~47%

6268-03-7结构式

6268-03-7

文献:Cortes-Salva, Michelle; Nguyen, Be-Lan; Cuevas, Javier; Pennypacker, Keith R.; Antilla, Jon C. Organic Letters, 2010 , vol. 12, # 6 p. 1316 - 1319

~36%

6268-03-7结构式

6268-03-7

文献:Reddy, N. Laxma; Hu, Lain-Yen; Cotter, Ronald E.; Fischer, James B.; Wong, Wen Jee; et al. Journal of Medicinal Chemistry, 1994 , vol. 37, # 2 p. 260 - 267

~%

6268-03-7结构式

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文献:Schering-Kahlbaum A.G. Patent: DE500161 , 1927 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 2338

~%

6268-03-7结构式

6268-03-7

文献:Naunton Journal of the Society of Chemical Industry, London, 1926 , vol. 45, p. 378 T Chem. Zentralbl., 1927 , vol. 98, # I p. 368

~%

6268-03-7结构式

6268-03-7

文献:Foerster Chemische Berichte, 1888 , vol. 21, p. 1870

~%

6268-03-7结构式

6268-03-7

文献:Schering-Kahlbaum A.G. Patent: DE571228 , 1925 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 18, p. 3070

~%

6268-03-7结构式

6268-03-7

文献:Schering-Kahlbaum A.G. Patent: DE500161 , 1927 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 2338

~%

6268-03-7结构式

6268-03-7

文献:Foerster Chemische Berichte, 1888 , vol. 21, p. 1870