4051-27-8

• 常用中文名：Pentitol,1,2:4,5-dianhydro-3-deoxy- (9CI)
• 常用英文名：Pentitol,1,2:4,5-dianhydro-3-deoxy- (9CI)
• CAS号：4051-27-8
• 分子式：C₅H₈O₂
• 分子量：100.11600
• 发布时间：2017-10-20 02:42:32
• 更新时间：2024-01-02 17:12:54

名称

• 英文名: 2-(oxiran-2-ylmethyl)oxirane
• 英文别名: 2,2'-Methylenebisoxirane; 2-(oxiranylmethyl)-oxirane; 1,4,5-Diepoxypentane; Oxirane,2'-methylenebis; 1,2,4,5-Diepoxy-pentan; 1,2,4,5-diepoxy-pentane; Pentane,1,2:4,5-diepoxy; 1,4-pentadienediepoxide; 1:4-Pentadiene dioxide; 1,2:4,5-dianhydro-3-deoxypentitol

物化性质

• 密度: 1.218g/cm3
• 沸点: 181ºC at 760mmHg
• 分子式: C₅H₈O₂
• 分子量: 100.11600
• 闪点: 60.9ºC
• 精确质量: 100.05200
• PSA: 25.06000
• LogP: 0.17410
• 蒸汽压: 1.18mmHg at 25°C
• 折射率: 1.504

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SA0370000 CAS REGISTRY NUMBER : 4051-27-8 LAST UPDATED : 199712 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C5-H8-O2 MOLECULAR WEIGHT : 100.13 WISWESSER LINE NOTATION : T3OTJ B1- BT3OTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 70 gm/kg/58W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 76 gm/kg/63W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application MUTATION DATA TEST SYSTEM : Rodent - rat DOSE/DURATION : 250 mg/kg REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,235,1951

合成路线

591-93-5 ~99% 4051-27-8

文献：Baylon, Christophe; Heck, Marie-Pierre; Mioskowski, Charles Journal of Organic Chemistry, 1999 , vol. 64, # 9 p. 3354 - 3360

6790-38-1 ~94% 4051-27-8

文献：Nozhnin; Mel'nik; Yegorova; Kryukov Petroleum Chemistry, 1997 , vol. 37, # 2 p. 156 - 160

2873-74-7 ~% 4051-27-8

文献：Schreiber, Stuart L.; Goulet, Mark T.; Schulte, Gayle Journal of the American Chemical Society, 1987 , vol. 109, # 15 p. 4718 - 4720

29548-85-4 ~% 4051-27-8

文献：Schreiber, Stuart L.; Goulet, Mark T.; Schulte, Gayle Journal of the American Chemical Society, 1987 , vol. 109, # 15 p. 4718 - 4720

591-93-5 ~0% 4051-27-8 6790-38-1

文献：Nozhnin; Mel'nik; Yegorova; Kryukov Petroleum Chemistry, 1997 , vol. 37, # 2 p. 156 - 160

上下游产品

上游产品  4
591-93-5 6790-38-1 2873-74-7 29548-85-4
下游产品  1
58534-88-6