65242-46-8

• 常用中文名：Epicholestanyl monosodium phosphate
• 常用英文名：Epicholestanyl monosodium phosphate
• CAS号：65242-46-8
• 分子式：C₂₇H₄₉NaO₄P+
• 分子量：491.63900
• 发布时间：2016-07-06 03:38:18
• 更新时间：2024-02-16 21:20:01

名称

• 英文名: Epicholestanyl monosodium phosphate

物化性质

• 密度: 1.09g/cm3
• 沸点: 561.1ºC at 760 mmHg
• 分子式: C₂₇H₄₉NaO₄P+
• 分子量: 491.63900
• 闪点: 293.2ºC
• 精确质量: 491.32700
• PSA: 76.57000
• LogP: 7.58560
• 折射率: 1.521

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : FZ6450000 CHEMICAL NAME : 3-alpha-Cholestanol, hydrogen phosphate, monosodium salt CAS REGISTRY NUMBER : 65242-46-8 LAST UPDATED : 199210 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C27-H48-O4-P.Na MOLECULAR WEIGHT : 490.71 WISWESSER LINE NOTATION : L E5 B666TJ A1 E1 FY1&3Y1&1 OOPWQ &-NA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >12 gm/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,521,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >20 gm/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,521,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 195 gm/kg/13W-I TOXIC EFFECTS : Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,521,1978 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 64 gm/kg SEX/DURATION : female 7-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,529,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 42664 mg/kg SEX/DURATION : female 7-14 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,529,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 96 gm/kg SEX/DURATION : female 7-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,529,1978