115436-74-3

• 常用中文名：ipazilide fumarate
• 常用英文名：ipazilide fumarate
• CAS号：115436-74-3
• 分子式：C₂₈H₃₄N₄O₅
• 分子量：506.59300
• 发布时间：2016-08-02 00:24:28
• 更新时间：2024-02-07 07:50:53

名称

• 英文名: (E)-but-2-enedioic acid,N-[3-(diethylamino)propyl]-2-(4,5-diphenylpyrazol-1-yl)acetamide
• 英文别名: IPAZILIDE FUMARATE; N-(3-(Diethylamino)propyl)-4,5-diphenyl-1H-pyrazole-1-acetamide (E)-2-butenedioate (1:1); Ipazilide fumarate (USAN); 1H-Pyrazole-1-acetamide,N-(3-(diethylamino)propyl)-4,5-diphenyl-,(E)-2-butenedioate (1:1); N-[3-(diethylamino)propyl]-2-(4,5-diphenyl-1H-pyrazol-1-yl)acetamide (2E)-but-2-enedioate

物化性质

• 沸点: 569.7ºC at 760mmHg
• 分子式: C₂₈H₃₄N₄O₅
• 分子量: 506.59300
• 闪点: 298.4ºC
• 精确质量: 506.25300
• PSA: 128.25000
• LogP: 4.61730
• 蒸汽压: 5.4E-13mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ4903600 CAS REGISTRY NUMBER : 115436-74-3 LAST UPDATED : 199403 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C24-H30-N4-O.C4-H4-O4 MOLECULAR WEIGHT : 506.66 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Cardiac - pulse rate increase, without fall in BP REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 18,581,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 29200 mg/kg/1Y-I TOXIC EFFECTS : Liver - changes in liver weight Endocrine - changes in thyroid weight Blood - changes in leukocyte (WBC) count REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 20,147,1993 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9280 mg/kg/29D-I TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - proteinuria Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 18,581,1992 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 870 mg/kg/29D-I TOXIC EFFECTS : Cardiac - pulse rate increase, without fall in BP Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 18,581,1992