62522-72-9

• 常用中文名：3-氟-2-羟基苯甲酸丙酯
• 常用英文名：3-Fluoro-2-hydroxypropyl=benzoate
• CAS号：62522-72-9
• 分子式：C₁₀H₁₁FO₃
• 分子量：198.19100
• 发布时间：2018-04-22 08:00:00
• 更新时间：2024-01-07 22:23:40

名称

• 中文名: 3-氟-2-羟基苯甲酸丙酯
• 英文名: (3-fluoro-2-hydroxypropyl) benzoate
• 英文别名: 3-fluoro-1,2-propanediol 1-O-benzoate; 1-Benzoyloxy-3-fluoropropan-2-ol; BENZOIC ACID,3-FLUORO-2-HYDROXYPROPYL ESTER; 1-Benzoyloxy-3-fluorpropan-2-ol

物化性质

• 密度: 1.21g/cm3
• 沸点: 326ºC at 760 mmHg
• 分子式: C₁₀H₁₁FO₃
• 分子量: 198.19100
• 闪点: 151ºC
• 精确质量: 198.06900
• PSA: 46.53000
• LogP: 1.17380
• 折射率: 1.509

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DH1320000 CHEMICAL NAME : Benzoic acid, 3-fluoro-2-hydroxypropyl ester CAS REGISTRY NUMBER : 62522-72-9 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H11-F-O3 MOLECULAR WEIGHT : 198.21 WISWESSER LINE NOTATION : F1YQ1OVR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,644,1977

合成路线

98760-25-9 ~43% 142545-49-1 62522-72-9

文献：Landini, Dario; Albanese, Domenico; Penso, Michele Tetrahedron, 1992 , vol. 48, # 20 p. 4163 - 4170

453-16-7 98-88-4 ~% 62522-72-9

文献：Pero,R.W. et al. Journal of Medicinal Chemistry, 1977 , vol. 20, p. 644 - 647