28768-32-3

• 常用中文名：N,N,N,N,-四环氧丙基-4,4-二氨基二苯甲烷
• 常用英文名：4,4'-Methylenebis(N,N-diglycidylaniline)
• CAS号：28768-32-3
• 分子式：C₂₅H₃₀N₂O₄
• 分子量：422.51700
• 发布时间：2018-12-29 12:35:58
• 更新时间：2024-01-03 13:06:03
• 下载msds

名称

• 中文名: N,N,N,N,-四环氧丙基-4,4-二氨基二苯甲烷
• 英文名: 4-[[4-[bis(oxiran-2-ylmethyl)amino]phenyl]methyl]-N,N-bis(oxiran-2-ylmethyl)aniline
• 中文别名: 4,4'-亚甲基双(N,N-二环丙氧基苯胺); N,N,N’,N’-四环氧丙基-4,4’-二氨基二苯甲烷; 4,4'-亚甲基二(N,N-二缩水甘油基苯胺)
• 英文别名: tetraglycidylmethylene dianiline; 4,4'-Methylenebis(N,N-diglycidylaniline); MFCD00661161; 4,4'-tetradiglycidyl diaminodiphenyl methane; N,N,N',N'-tetraglycidyl-4,4'-diaminodiphenylmethane; EINECS 249-204-3; Tetraglycidyl diaminosiphenyl methane

物化性质

• 密度: 1.15
• 沸点: 619.3ºC at 760mmHg
• 分子式: C₂₅H₃₀N₂O₄
• 分子量: 422.51700
• 闪点: 113ºC
• 精确质量: 422.22100
• PSA: 56.60000
• LogP: 2.48540
• 外观性状: 液体;Light yellow to Brown clear liquid
• 蒸汽压: 2.9E-15mmHg at 25°C
• 折射率: 1.601
• 储存条件:

  保持贮藏器密封

  放入紧密的贮藏器内，储存在阴凉，干燥的地方

• 稳定性:

  遵照规定使用和储存则不会分解。

• 计算化学:

  1.疏水参数计算参考值（XlogP）:2.9

  2.氢键供体数量:0

  3.氢键受体数量:6

  4.可旋转化学键数量:12

  5.互变异构体数量:无

  6.拓扑分子极性表面积56.6

  7.重原子数量:31

  8.表面电荷:0

  9.复杂度:512

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:4

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：1.15

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：无可用

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：1.601

  8. 闪点（ºC）：>113

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：无可用

MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers : 4,4′-Methylenebis(N,N-diglycidylaniline) Product name REACH No.: A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. CAS-No.: 28768-32-3 Relevant identified uses of the substance or mixture and uses advised against Identified uses: Laboratory chemicals, Manufacture of substances SECTION 2: Hazards identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Skin sensitisation (Category 1), H317 Chronic aquatic toxicity (Category 2), H411 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/EC Xi, N Irritant, Dangerous for the R43, R51/53 environment For the full text of the R-phrases mentioned in this Section, see Section 16. Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal wordWarning Hazard statement(s) H317May cause an allergic skin reaction. H411Toxic to aquatic life with long lasting effects. Precautionary statement(s) P273Avoid release to the environment. P280Wear protective gloves. Supplemental Hazardnone Statements Other hazards - none SECTION 3: Composition/information on ingredients Substances Formula: C25H30N2O4 Molecular Weight: 422,52 g/mol CAS-No.: 28768-32-3 EC-No.: 249-204-3 Hazardous ingredients according to Regulation (EC) No 1272/2008 ComponentClassificationConcentration 4,4'-Methylenebis[N,N-bis(2,3-epoxypropyl)aniline] CAS-No.28768-32-3Skin Sens. 1; Aquatic Chronic <= 100 % EC-No.249-204-32; H317, H411 Hazardous ingredients according to Directive 1999/45/EC ComponentClassificationConcentration 4,4'-Methylenebis[N,N-bis(2,3-epoxypropyl)aniline] CAS-No.28768-32-3Xi, N, R43 - R51/53<= 100 % EC-No.249-204-3 For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16 SECTION 4: First aid measures Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 Indication of any immediate medical attention and special treatment needed no data available SECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available SECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. For personal protection see section 8. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. SECTION 7: Handling and storage Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Heat sensitive. Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated SECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. SECTION 9: Physical and chemical properties Information on basic physical and chemical properties a) AppearanceForm: viscous liquid Colour: yellow b) Odourno data available c) Odour Thresholdno data available d) pH> 7,1 - < 7,3 at >= 10 mg/l at 20 °C e) Melting point/freezingFreezing point/ range: -13,2 °C - OECD Test Guideline 102 point f) Initial boiling point and no data available boiling range g) Flash point113 °C - closed cup h) Evapouration rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative density1,15 g/cm3 at 25 °C n) Water solubilityca.0,0092 g/l at 20 °C - OECD Test Guideline 105 - slightly soluble o) Partition coefficient: n- log Pow: ca.2,12 at 22 °C octanol/water p) Auto-ignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesNot explosive t) Oxidizing propertiesno data available Other safety information Surface tensionca.61,8 mN/m at 19,8 °C SECTION 10: Stability and reactivity Reactivity no data available Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions no data available Conditions to avoid Heat. Incompatible materials Oxidizing agentsStrong oxidizing agents, acids, Bases Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5 SECTION 11: Toxicological information Information on toxicological effects Acute toxicity LD50 Oral - rat - male and female - > 5.000 mg/kg (OECD Test Guideline 401) Skin corrosion/irritation Skin - rabbit Result: Mild skin irritation - 4 h (OECD Test Guideline 404) Serious eye damage/eye irritation no data available Respiratory or skin sensitisation in vivo assay - mouse Result: May cause sensitisation by skin contact. (OECD Test Guideline 429) Germ cell mutagenicity no data available Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information Repeated dose toxicity - rat - male and female - Oral - No observed adverse effect level - 50 mg/kg RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological information Toxicity no data available Toxicity to daphnia and semi-static test EC50 - Daphnia magna (Water flea) - ca. 6,7 mg/l - 48 h other aquatic(OECD Test Guideline 202) invertebrates Toxicity to algaestatic test EC50 - Pseudokirchneriella subcapitata (Selenastrum capricornutum) - ca. 4,8 mg/l - 72 h (OECD Test Guideline 201) Persistence and degradability Biodegradabilityaerobic - Exposure time 28 d Result: 48 % - Not readily biodegradable. (OECD Test Guideline 301F) Remarks: The 10 day time window criterion is not fulfilled. Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects Toxic to aquatic life with long lasting effects. SECTION 13: Disposal considerations Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information UN number ADR/RID: 3082IMDG: 3082IATA: 3082 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (4,4'-Methylenebis[N,N- bis(2,3-epoxypropyl)aniline]) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (4,4'-Methylenebis[N,N- bis(2,3-epoxypropyl)aniline]) IATA:Environmentally hazardous substance, liquid, n.o.s. (4,4'-Methylenebis[N,N-bis(2,3- epoxypropyl)aniline]) Transport hazard class(es) ADR/RID: 9IMDG: 9IATA: 9 Packaging group ADR/RID: IIIIMDG: IIIIATA: III Environmental hazards ADR/RID: yesIMDG Marine pollutant: yesIATA: yes Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids. SECTION 15: Regulatory information This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment For this product a chemical safety assessment was not carried out SECTION 16: Other information Full text of H-Statements referred to under sections 2 and 3. Aquatic ChronicChronic aquatic toxicity H317May cause an allergic skin reaction. H411Toxic to aquatic life with long lasting effects. Skin Sens.Skin sensitisation Full text of R-phrases referred to under sections 2 and 3 NDangerous for the environment XiIrritant R43May cause sensitisation by skin contact. R51/53Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Further information Copyright 2014 Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

毒性和生态

生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。

安全

• 符号: GHS07, GHS09
• 信号词: Warning
• 危害声明: H317-H411
• 警示性声明: P273-P280
• 个人防护装备: Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R43
• 安全声明 (欧洲): S36/37
• 危险品运输编码: UN 3082 9 / PGIII
• WGK德国: 2.0
• 海关编码: 2921590090

海关

海关编码	2921590090
中文概述	2921590090. 其他芳香多胺及衍生物及它们的盐. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%