CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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SG9275000
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CHEMICAL NAME :
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Phenethylamine, alpha-allyl-, hydrochloride
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CAS REGISTRY NUMBER :
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4255-24-7
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LAST UPDATED :
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199112
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C11-H15-N.Cl-H
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MOLECULAR WEIGHT :
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197.73
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WISWESSER LINE NOTATION :
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1U2YZ1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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680 mg/kg
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TOXIC EFFECTS :
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Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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280 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in psychophysiological tests
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 159,442,1966
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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43 mg/kg
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TOXIC EFFECTS :
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Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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175 mg/kg
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TOXIC EFFECTS :
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Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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260 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 6,96,1966
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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30 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,332,1972
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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172 mg/kg
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TOXIC EFFECTS :
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Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 172,251,1968
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