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1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

更新时间:2024-01-09 12:03:14

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式
1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式
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常用名 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid 英文名 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
CAS号 108138-27-8 分子量 403.35500
密度 1.48g/cm3 沸点 611ºC at 760 mmHg
分子式 C20H16F3N3O3 熔点 N/A
MSDS N/A 闪点 323.3ºC

 名称

英文名 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
英文别名 更多

 物理化学性质

密度 1.48g/cm3
沸点 611ºC at 760 mmHg
分子式 C20H16F3N3O3
分子量 403.35500
闪点 323.3ºC
精确质量 403.11400
PSA 74.57000
LogP 2.90960
蒸汽压 8.74E-16mmHg at 25°C
折射率 1.62

 合成线路

~46%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid结构式

1-(2,4-difluoro...

108138-27-8

文献:Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

 英文别名

t 1814