1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

Modify Date: 2024-01-09 12:03:14

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid structure	Common Name	1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
	CAS Number	108138-27-8	Molecular Weight	403.35500
	Density	1.48g/cm3	Boiling Point	611ºC at 760 mmHg
	Molecular Formula	C₂₀H₁₆F₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	323.3ºC

Name	1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
Synonym	More Synonyms

Density	1.48g/cm3
Boiling Point	611ºC at 760 mmHg
Molecular Formula	C₂₀H₁₆F₃N₃O₃
Molecular Weight	403.35500
Flash Point	323.3ºC
Exact Mass	403.11400
PSA	74.57000
LogP	2.90960
Vapour Pressure	8.74E-16mmHg at 25°C
Index of Refraction	1.62

Piperazine structure

Piperazine

CAS#:110-85-0

1-(2,4-DIFLUOROPHENYL)-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID structure

1-(2,4-DIFLUORO...

CAS#:103995-01-3

~46%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

2,4-Difluoroaniline structure

2,4-Difluoroaniline

CAS#:367-25-9

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

2,4,5-Trifluorobenzoic acid structure

2,4,5-Trifluoro...

CAS#:446-17-3

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1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

Ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate structure

Ethyl 3-oxo-3-(...

CAS#:98349-24-7

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1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid ethyl ester structure

6,7-difluoro-1-...

CAS#:108138-17-6

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1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

ethyl 3-(2,4-difluoroanilino)-2-(2,4,5-trifluorobenzoyl)acrylate structure

ethyl 3-(2,4-di...

CAS#:108115-67-9

~%

1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Structure

1-(2,4-difluoro...

CAS#:108138-27-8

Literature: Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

Precursor 7
CAS#:110-85-0 Piperazine CAS#:103995-01-3 1-(2,4-DIFLUORO... CAS#:367-25-9 2,4-Difluoroaniline CAS#:446-17-3 2,4,5-Trifluoro...
CAS#:98349-24-7 Ethyl 3-oxo-3-(... CAS#:108138-17-6 6,7-difluoro-1-... CAS#:108115-67-9 ethyl 3-(2,4-di...
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