UCN-01

更新时间：2024-01-09 19:31:26

UCN-01结构式	常用名	UCN-01	英文名	UCN-01
	CAS号	112953-11-4	分子量	482.53000
	密度	1.63g/cm3	沸点	705.7ºC at 760mmHg
	分子式	C₂₈H₂₆N₄O₄	熔点	N/A
	MSDS	中文版美版	闪点	380.6ºC

UCN-01用途

UCN-01 (7-Hydroxystaurosporine.

英文名	7-Hydroxystaurosporine
英文别名	更多

密度	1.63g/cm3
沸点	705.7ºC at 760mmHg
分子式	C₂₈H₂₆N₄O₄
分子量	482.53000
闪点	380.6ºC
精确质量	482.19500
PSA	89.68000
LogP	4.56460
外观性状	浅黄色固体
蒸汽压	6.64E-21mmHg at 25°C
折射率	1.827
储存条件	-20°C

UCN-01毒性英文版

危险品运输编码	NONH for all modes of transport
RTECS号	KC6600010

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

BMC Cancer 15 , 17, (2015)

DNAX accessory molecule-1 (DNAM-1) is an activating receptor constitutively expressed by macrophages/dendritic cells and by T lymphocytes and Natural Killer (NK) cells, having an important role in ant...

Induction of DNA damage and G2 cell cycle arrest by diepoxybutane through the activation of the Chk1-dependent pathway in mouse germ cells.

Chem. Res. Toxicol. 28(3) , 518-31, (2015)

1,2:3,4-Diepoxybutane (DEB) is a major carcinogenic metabolite of 1,3-butadiene (BD), which has been shown to cause DNA strand breaks in cells through its potential genotoxicity. The adverse effect of...

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.

Autophagy 11 , 1373-88, (2015)

Oncogenic mutation of KRAS (Kirsten rat sarcoma viral oncogene homolog) in colorectal cancer (CRC) confers resistance to both chemotherapy and EGFR (epidermal growth factor receptor)-targeted therapy....

UCN-01

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