syringomycin E

更新时间:2024-01-11 17:08:01

syringomycin E结构式
syringomycin E结构式
品牌特惠专场
常用名 syringomycin E 英文名 syringomycin E
CAS号 124888-22-8 分子量 1225.78000
密度 1.47g/cm3 沸点 N/A
分子式 C53H85ClN14O17 熔点 N/A
MSDS 中文版 美版 闪点 N/A

 syringomycin E用途

tip
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雪兰莪霉素E是一种抗真菌的环状脂肪去甲肽。雪兰莪霉素E通过与质膜的相互作用表现出对酿酒酵母的生长抑制。丁香霉素E导致K+流出、Ca2+内流和膜电位变化,并与通道形成相关[1][2]。

 syringomycin E名称

英文名 syringomycin E
英文别名 更多

 syringomycin E生物活性

描述 雪兰莪霉素E是一种抗真菌的环状脂肪去甲肽。雪兰莪霉素E通过与质膜的相互作用表现出对酿酒酵母的生长抑制。丁香霉素E导致K+流出、Ca2+内流和膜电位变化,并与通道形成相关[1][2]。
相关类别
体外研究 雪林霉素E(0.5μg/mL,1μg/mL;48小时)对酿酒酵母菌株 第33章和 第56页有抑制作用[1]。 雪林霉素E是一种离子通道型,对电势跨膜分布的变化敏感[2]。
参考文献

[1]. Stock SD, et al. Syringomycin E inhibition of Saccharomyces cerevisiae: requirement for biosynthesis of sphingolipids with very-long-chain fatty acids and mannose- and phosphoinositol-containing head groups. Antimicrob Agents Chemother. 2000 May;44(5):1174-80.  

[2]. Efimova SS, et al. Alkaloids Modulate the Functioning of Ion Channels Produced by Antimicrobial Agents via an Influence on the Lipid Host. Front Cell Dev Biol. 2020 Jun 30;8:537.  

 syringomycin E物理化学性质

密度 1.47g/cm3
分子式 C53H85ClN14O17
分子量 1225.78000
精确质量 1224.59000
PSA 522.86000
LogP 0.18720
折射率 1.641

 syringomycin E安全信息

个人防护装备 Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
危险品运输编码 NONH for all modes of transport

 syringomycin E文献24

更多文献
Change in activity of serine palmitoyltransferase affects sensitivity to syringomycin E in yeast Saccharomyces cerevisiae.

FEMS Microbiol. Lett. 358(1) , 64-71, (2014)

Syringomycin E is a cyclic lipodepsipeptide produced by strains of the plant bacterium Pseudomonas syringae pv. syringae. Genetic studies involving the yeast Saccharomyces cerevisiae have revealed tha...

Effect of agents modifying the membrane dipole potential on properties of syringomycin E channels.

Langmuir 23(13) , 6889-92, (2007)

We evaluated the effect of agents modifying the membrane dipole potential: phloretin, 6-ketocholestanol and RH 421 on the properties of single channels formed by lipodepsipeptide syringomycin E (SRE) ...

[Transport of large organic ions through syringomycin channels in the membranes containing dipole modifiers].

Tsitologiia 53(5) , 450-6, (2011)

The effect of the membrane dipole potential (Phid) on a conductance and a steady-state number of functioning channels formed by cyclic lipodepsipeptide syringomycin E (SRE) in bilayer lipid membranes ...

 syringomycin E英文别名

SYRINGOMYCIN E FROM PSEUDOMONAS SYRINGAE B-301D
syringomycin-E