Z-LLF-CHO

• 常用名: Z-LLF-CHO
• 英文名: Z-LLF-CHO
• CAS号: 133429-58-0
• 分子量: 509.64
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₉N₃O₅
• 熔点: N/A
• 闪点: N/A

Z-LLF-CHO用途

Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) 是垂体多催化蛋白酶复合物的胰凝乳蛋白酶样活性 (chymotrypsin-like activity) 的有效抑制剂 (Ki = 460 nM)。Z-LLF-CHONF-κB 也是一种 NF-κB 核转位抑制剂。

Z-LLF-CHO名称

• 英文名: Z-LLF-CHO

Z-LLF-CHO生物活性

• 描述: Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) 是垂体多催化蛋白酶复合物的胰凝乳蛋白酶样活性 (chymotrypsin-like activity) 的有效抑制剂 (Ki = 460 nM)。Z-LLF-CHONF-κB 也是一种 NF-κB 核转位抑制剂。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 代谢酶/蛋白酶 >> 蛋白酶体
• 参考文献:

  [1]. Orlowski M, et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. Biochemistry. 1993 Feb 16;32(6):1563-72.

  [2]. Ding L, et al. Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells. Int J Biochem Cell Biol. 2005 Sep;37(9):1881-9.

Z-LLF-CHO物理化学性质

• 分子式: C₂₉H₃₉N₃O₅
• 分子量: 509.64