BM212

• 常用名: BM212
• 英文名: BM212
• CAS号: 146204-42-4
• 分子量: 414.371
• 密度: 1.2±0.1 g/cm3
• 沸点: 528.3±50.0 °C at 760 mmHg
• 分子式: C₂₃H₂₅Cl₂N₃
• 熔点: N/A
• 闪点: 273.3±30.1 °C

BM212用途

发挥杀菌活性与细胞内细菌驻留,完全抑制胞内分枝杆菌。

BM212名称

• 中文名: BM212
• 英文名: 1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine

BM212生物活性

• 描述: 发挥杀菌活性与细胞内细菌驻留,完全抑制胞内分枝杆菌。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2)

  [2]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

  [3]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains.

BM212物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 528.3±50.0 °C at 760 mmHg
• 分子式: C₂₃H₂₅Cl₂N₃
• 分子量: 414.371
• 闪点: 273.3±30.1 °C
• 精确质量: 413.142548
• PSA: 11.41000
• LogP: 5.32
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.622
• 储存条件: 2-8℃

BM212英文别名

• unii-u9hsu4gzwl
• 1-{[1,5-Bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl}-4-methylpiperazine
• 1-{[1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine
• Piperazine, 1-[[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl]-4-methyl-
• bm212