LYN-1604 盐酸盐结构式
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常用名 | LYN-1604 盐酸盐 | 英文名 | LYN-1604 hydrochloride |
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CAS号 | 2216753-86-3 | 分子量 | 621.080 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C33H44Cl3N3O2 | 熔点 | N/A | |
MSDS | N/A | 闪点 | N/A |
LYN-1604 盐酸盐用途LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. LYN-1604 could induce cell death, associated with autophagy by the ULK complex (ULK1-mATG13-FIP200-ATG101) in MDA-MB-231 cells. To further explore LYN-1604-induced autophagic mechanisms, we found some potential ULK1 interactors, such as ATF3, RAD21, and caspase3, by performing comparative microarray analysis. LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. |
中文名 | LYN-1604 盐酸盐 |
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英文名 | 1-{4-[2-(2,4-Dichlorophenyl)-2-(2-naphthylmethoxy)ethyl]-1-piperazinyl}-2-(diisobutylamino)ethanone hydrochloride (1:1) |
英文别名 | 更多 |
分子式 | C33H44Cl3N3O2 |
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分子量 | 621.080 |
精确质量 | 619.249939 |
储存条件 | 2-8°C,存于惰性气体中 |
危害码 (欧洲) | Xn |
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Ethanone, 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-, hydrochloride (1:1) |
1-{4-[2-(2,4-Dichlorophenyl)-2-(2-naphthylmethoxy)ethyl]-1-piperazinyl}-2-(diisobutylamino)ethanone hydrochloride (1:1) |
MFCD31630830 |