LYN-1604 hydrochloride

Modify Date: 2024-04-08 18:53:02

LYN-1604 hydrochloride Structure
LYN-1604 hydrochloride structure
Common Name LYN-1604 hydrochloride
CAS Number 2216753-86-3 Molecular Weight 621.080
Density N/A Boiling Point N/A
Molecular Formula C33H44Cl3N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LYN-1604 hydrochloride


LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. LYN-1604 could induce cell death, associated with autophagy by the ULK complex (ULK1-mATG13-FIP200-ATG101) in MDA-MB-231 cells. To further explore LYN-1604-induced autophagic mechanisms, we found some potential ULK1 interactors, such as ATF3, RAD21, and caspase3, by performing comparative microarray analysis. LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

 Names

Name 1-{4-[2-(2,4-Dichlorophenyl)-2-(2-naphthylmethoxy)ethyl]-1-piperazinyl}-2-(diisobutylamino)ethanone hydrochloride (1:1)
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C33H44Cl3N3O2
Molecular Weight 621.080
Exact Mass 619.249939

 Safety Information

Hazard Codes Xn

 Synonyms

Ethanone, 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-, hydrochloride (1:1)
1-{4-[2-(2,4-Dichlorophenyl)-2-(2-naphthylmethoxy)ethyl]-1-piperazinyl}-2-(diisobutylamino)ethanone hydrochloride (1:1)
MFCD31630830
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