依托红霉素

更新时间：2024-01-02 16:37:20

依托红霉素结构式	常用名	依托红霉素	英文名	Erythromycin Estolate
	CAS号	3521-62-8	分子量	1000.324
	密度	1.0053 (rough estimate)	沸点	827.7ºC at 760 mmHg
	分子式	C₅₂H₉₇NO₁₈S	熔点	135-140ºC dec.
	MSDS	中文版美版	闪点	454.4ºC
	符号	GHS07, GHS08	信号词	Danger

依托红霉素用途

Erythromycin estolate 是红霉素衍生物,是一种大环内酯类抗生素,用于治疗多种细菌感染。Erythromycin estolate 引起数例肝损伤,主要包括胆汁淤积性肝炎。Erythromycin estolate 的毒性与其对胆汁酸运输的抑制作用有关。

中文名	无味红霉素
英文名	erythromycin estolate
中文别名	红霉素丙酸酯十二烷基硫酸盐 \| 依托红霉素 \| 依托红霉素 \| 红霉素月桂酸酯
英文别名	更多

描述	Erythromycin estolate 是红霉素衍生物,是一种大环内酯类抗生素,用于治疗多种细菌感染。Erythromycin estolate 引起数例肝损伤,主要包括胆汁淤积性肝炎。Erythromycin estolate 的毒性与其对胆汁酸运输的抑制作用有关。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
参考文献	[1]. David E. Kleiner, et al. Learn more about Erythromycin Estolate. Biomaterials and Medical Device - Associated Infections, 2015 [2]. Lu X, et al. Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat. Food Chem Toxicol. 2014 Mar;65:343-55.

描述

相关类别

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

参考文献

[1]. David E. Kleiner, et al. Learn more about Erythromycin Estolate. Biomaterials and Medical Device - Associated Infections, 2015

[2]. Lu X, et al. Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat. Food Chem Toxicol. 2014 Mar;65:343-55.

密度	1.0053 (rough estimate)
沸点	827.7ºC at 760 mmHg
熔点	135-140ºC dec.
分子式	C₅₂H₉₇NO₁₈S
分子量	1000.324
闪点	454.4ºC
精确质量	999.616394
PSA	271.96000
LogP	7.55400
外观性状	长针状
折射率	1.6550 (estimate)
储存条件	-20°C Freezer
水溶解性	chloroform: soluble4.0ML, clear, colorless (200 mg + 4.0 mL Chloroform)

依托红霉素MSDS英文版

依托红霉素毒性英文版

符号	GHS07, GHS08
信号词	Danger
危害声明	H302-H317-H334
警示性声明	P261-P280-P342 + P311
危害码 (欧洲)	Xn:Harmful
风险声明 (欧洲)	R22;R42/43
安全声明 (欧洲)	S22-S36
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	KF5775000
海关编码	29419000

十二烷基硫酸钠

151-21-3

红霉素

114-07-8

依托红霉素

3521-62-8

文献：Skin Pharmacology, , vol. 8, # 6 p. 319 - 325

依托红霉素上游产品 2
CAS号151-21-3 十二烷基硫酸钠 CAS号114-07-8 红霉素
依托红霉素下游产品 0

Protective effect of Livex, a herbal formulation against erythromycin estolate induced hepatotoxicity in rats.

J. Ethnopharmacol. 57(3) , 161-7, (1997)

Livex, a compound herbal formulation, was investigated for its possible hepatoprotective effect in Wistar rats against erythromycin estolate induced toxicity. Oral administration of Livex significantl...

Preparation and characterization of biodegradable poly(l-lactide)/poly(ethylene glycol) microcapsules containing erythromycin by emulsion solvent evaporation technique.

J. Colloid. Interface Sci. 271(2) , 336-41, (2004)

In this work, the producing of a biodegradable poly(l-lactide) (PLA)/poly(ethylene glycol) (PEG) microcapsule by emulsion solvent evaporation method was investigated. The effect of PEG segments added ...

Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals.

Am. J. Vet. Res. 61(8) , 914-9, (2000)

To determine pharmacokinetics and plasma concentrations of erythromycin and related compounds after intragastric administration of erythromycin phosphate and erythromycin estolate to healthy foals.11 ...

Erythromycin Estolate

Erythromycin 2'-propionate dodecyl sulfate

Erythromycin 2′-propionate dodecyl sulfate

Dodecyl hydrogen sulfate - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1)

Erythromycin 2-Propionate Dodecyl Sulfate