甲醇中喷布特罗溶液标准物质结构式
|
常用名 | 甲醇中喷布特罗溶液标准物质 | 英文名 | Penbutolol sulfate |
---|---|---|---|---|
CAS号 | 38363-32-5 | 分子量 | 340.47 | |
密度 | N/A | 沸点 | 438.2ºC at 760mmHg | |
分子式 | C18H29NO2.1/2H2O4S | 熔点 | 216-218℃ (Decomposition) | |
MSDS | N/A | 闪点 | 218.8ºC |
甲醇中喷布特罗溶液标准物质用途Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。 |
中文名 | 硫酸喷布洛尔 |
---|---|
英文名 | Penbutolol sulfate |
中文别名 | 喷布洛尔硫酸盐 |
英文别名 | 更多 |
描述 | Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。 |
---|---|
相关类别 |
沸点 | 438.2ºC at 760mmHg |
---|---|
熔点 | 216-218℃ (Decomposition) |
分子式 | C18H29NO2.1/2H2O4S |
分子量 | 340.47 |
闪点 | 218.8ºC |
PSA | 41.49000 |
LogP | 3.86290 |
储存条件 | 2-8°C |
危害码 (欧洲) | Xn |
---|---|
危险品运输编码 | NONH for all modes of transport |
5-HT receptor subtypes involved in the spinal antinociceptive effect of acetaminophen in rats.
Eur. J. Pharmacol. 432(1) , 1-7, (2001) The present study was designed to investigate which subtype of spinal 5-HT receptors were involved in acetaminophen-induced antinociception using the paw-pressure test. Propacetamol (prodrug of acetam... |
|
Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor.
Brain Res. 835(2) , 224-8, (1999) Serotonin (5-hydroxytryptamine, 5-HT) autoreceptors may desensitize during prolonged administration of antidepressant drugs. If autoreceptors desensitize, their inhibitory influence on extracellular 5... |
|
Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain.
J. Neurochem. 75(2) , 755-62, (2000) There is considerable interest in the use of drugs that selectively block presynaptic (somatodendritic) serotonin 5-HT(1A) receptors for the adjunctive treatment of major depressive disorder. The 5-HT... |
Penbutolol Sulfate |