长春西汀杂质B
长春西汀杂质B结构式
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常用名 | 长春西汀杂质B | 英文名 | Apovincamine |
|---|---|---|---|---|
| CAS号 | 4880-92-6 | 分子量 | 336.42700 | |
| 密度 | 1.3g/cm3 | 沸点 | 405.7ºC at 760mmHg | |
| 分子式 | C21H24N2O2 | 熔点 | 160-162℃ | |
| MSDS | N/A | 闪点 | 199.1ºC |
长春西汀杂质B用途Apovincamine (cis-Apovincamine) 是一种吲哚生物碱,从马来西亚的 Alstonia pneumatophore (Apocynaceae) 分离出来的。Apovincamine 显示抗黑色素生成活性。 |
| 中文名 | 阿扑长春胺 |
|---|---|
| 英文名 | Apovincamine |
| 中文别名 | 长春西汀杂质B |
| 英文别名 | 更多 |
| 描述 | Apovincamine (cis-Apovincamine) 是一种吲哚生物碱,从马来西亚的 Alstonia pneumatophore (Apocynaceae) 分离出来的。Apovincamine 显示抗黑色素生成活性。 |
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| 相关类别 | |
| 体外研究 | 载脂蛋白(顺式载脂蛋白胺；6.3、12.5、25、50、100μM)剂量依赖性抑制细胞活性,IC50为49.8μM,并在B16小鼠黑色素瘤细胞中显示抗黑素生成[1]。 |
| 参考文献 |
| 密度 | 1.3g/cm3 |
|---|---|
| 沸点 | 405.7ºC at 760mmHg |
| 熔点 | 160-162℃ |
| 分子式 | C21H24N2O2 |
| 分子量 | 336.42700 |
| 闪点 | 199.1ºC |
| 精确质量 | 336.18400 |
| PSA | 34.47000 |
| LogP | 3.69610 |
| 折射率 | 1.678 |
| 危险品运输编码 | NONH for all modes of transport |
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| 长春西汀杂质B上游产品 0 | |
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| 长春西汀杂质B下游产品 1 | |
CAS号42971-09-5|
Effects of aging and vincamine derivatives on pericapillary microenvironment: stereological characterization of the cerebral capillary network.
Neurobiol. Aging 11(1) , 39-46, (1990) Changes in the pericapillary microenvironment of adult (18-month-old) and senescent (27 1/2-month-old) Fischer-344 rats treated for 6 weeks with daily IP injections of brovincamine or apovincamine (0,... |
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Alpneumines A-H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora.
Bioorg. Med. Chem. 18(12) , 4415-21, (2010) Eight new indole alkaloids, alpneumines A-H (1-8) were isolated from the Malaysian Alstonia pneumatophora (Apocynaceae) and their structures were determined by MS and 2D NMR spectroscopic methods. Alp... |
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Synthesis of vinca alkaloids and related compounds. Part 84. Sulfonamide derivatives of some vinca alkaloids with cardiovascular activity.
Arch. Pharm. (Weinheim) 330(6) , 190-8, (1997) (+)-Vincamine (1) and (+)-vinpocetine (2) were chlorosulfonylated and the resulting sulfonyl chloride isomers (3-6) were transformed into sulfonamides (7-10). The ester group of sulfonamides was modif... |
| Apo-14,15-dehydrovincamine |
| 14,15-dehydrovincamine |
| Apovincamina [spanish] |
| eburnamenine-14-carboxylic acid methyl ester |
| Apovincaminum [latin] |
| Apovincaminum |
| Vinpocetine impurity B |
| Apovincaminic acid methyl |
| (3S,16S)-Apovincaminsaeure |
| Apovincamina |
| (+)-trans-Cavinton |
