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依曲替酯

更新时间:2024-01-08 21:17:23

依曲替酯结构式
依曲替酯结构式
品牌特惠专场
常用名 依曲替酯 英文名 Etretinate
CAS号 54350-48-0 分子量 354.483
密度 1.0±0.1 g/cm3 沸点 506.4±38.0 °C at 760 mmHg
分子式 C23H30O3 熔点 104-105ºC
MSDS N/A 闪点 219.4±21.4 °C

 依曲替酯用途


Etretinate(Ro 10-9359)是一用于治疗银屑病的药物,临床上已被acitretin取代使用。

 依曲替酯名称

中文名 依曲替酯
英文名 etretinate
中文别名 替维甲 | 阿维A酯 | 全反式-9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-壬四烯酸乙酯
英文别名 更多

 依曲替酯生物活性

描述 Etretinate(Ro 10-9359)是一用于治疗银屑病的药物,临床上已被acitretin取代使用。
相关类别

 依曲替酯物理化学性质

密度 1.0±0.1 g/cm3
沸点 506.4±38.0 °C at 760 mmHg
熔点 104-105ºC
分子式 C23H30O3
分子量 354.483
闪点 219.4±21.4 °C
精确质量 354.219482
PSA 35.53000
LogP 6.77
外观性状 结晶固体
蒸汽压 0.0±1.3 mmHg at 25°C
折射率 1.544
储存条件 Amber Vial, -20°C Freezer

 依曲替酯毒性和生态

 依曲替酯安全信息

危害码 (欧洲) Xn
危险品运输编码 NONH for all modes of transport

 依曲替酯文献25

更多文献
Systemic retinoids in the management of ichthyoses and related skin types.

Dermatol. Ther. 26(1) , 26-38, (2013)

The term retinoid includes both natural and synthetic derivatives of vitamin A. Retinoid-containing treatments have been used since ~1550BC by the early Egyptians. Treatment of ichthyosiform disorders...

The effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs.

Expert Opin. Drug Metab. Toxicol. 8(8) , 959-72, (2012)

Alcohol has long been suspected to be a triggering and precipitating factor of psoriasis. Alcohol misuse is common in patients with moderate-to-severe psoriasis and appears to impair treatment outcome...

Generalized pustular psoriasis in a child: observation of long-term combination therapy with etretinate and calcipotriol for 16 years.

Pediatr. Dermatol. 29(2) , 206-8, (2012)

Generalized pustular psoriasis (GPP) is a rare condition in young children. It is difficult to treat and may require long-term systemic therapy. We report the long-term course of a 3-year-old boy whos...

 依曲替酯英文别名

ethyl (all-E)-9-(4-methyoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester
Retinoid
9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester
Ethyl etrinoate
Ro 10-9359
Etretinatum [INN-Latin]
Etretinato
ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
Etretinatum
ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
EINECS 259-119-3
MFCD00866624
Ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
Etretinato [INN-Spanish]
Tegison
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