夫西地酸

• 常用名: 夫西地酸
• 英文名: fusidic acid
• CAS号: 6990-06-3
• 分子量: 516.709
• 密度: 1.2±0.1 g/cm3
• 沸点: 635.6±55.0 °C at 760 mmHg
• 分子式: C₃₁H₄₈O₆
• 熔点: 190-192ºC
• 闪点: 197.7±25.0 °C
• 符号: GHS07
• 信号词: Warning

夫西地酸用途

Fusidic acid (Fusidate) 是一种抑菌抗生素。

夫西地酸名称

• 中文名: 夫西地酸
• 英文名: fusidic acid
• 中文别名: 褐霉酸

夫西地酸生物活性

• 描述: Fusidic acid (Fusidate) 是一种抑菌抗生素。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点:

  Bacterial[1][2][3]

• 参考文献:

  [1]. Falagas ME, et al. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther. 2008 Oct;6(5):593-600.

  [2]. Leclercq R, et al. In vitro activity of fusidic acid against streptococci isolated from skin and soft tissue infections. J Antimicrob Chemother. 2000 Jan;45(1):27-9.

  [3]. Spelman D, et al. Fusidic acid in skin and soft tissue infections. Int J Antimicrob Agents. 1999 Aug;12 Suppl 2:S59-66.

夫西地酸物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 635.6±55.0 °C at 760 mmHg
• 熔点: 190-192ºC
• 分子式: C₃₁H₄₈O₆
• 分子量: 516.709
• 闪点: 197.7±25.0 °C
• 精确质量: 516.345093
• PSA: 104.06000
• LogP: 6.41
• 外观性状: 白色固体
• 蒸汽压: 0.0±4.2 mmHg at 25°C
• 折射率: 1.558
• 储存条件: 2-8°C
• 水溶解性: 水溶性：实际上不溶；可溶于：氯仿,醇,丙酮,二噁烷；极微溶：乙醚

夫西地酸毒性和生态

夫西地酸安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 警示性声明: P301 + P312 + P330
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): 36
• 危险品运输编码: NONH for all modes of transport
• RTECS号: RC1350000
• 海关编码: 2942000000

夫西地酸海关

• 海关编码: 2942000000

夫西地酸英文别名

• (2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• Fucidic acid
• Fusidate sodium
• EINECS 230-256-0
• fusidic acid
• Fusidin
• FUCIDIN
• (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• Fusidate
• 5-Heptenoic acid, 2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methyl-, (2Z)-
• Ramycin
• fusdic acid
• (3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,14-trimethyl-18-norcholesta-17,24-dien-21-oic acid
• Fucithalmic
• Fucidin acid
• MFCD00865135
• 3,11,16-Trihydroxy-4,8,10,14-tetramethyl-17-(1'-carboxyisohept-4'-enylidene)cyclopentanoperhydrophenanthrene 16-Acetate
• FusidicAcid
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• (3a,4a,8a,9b,11a,13a,14b,16b,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid
• Diethanolamine fusidate
• Fusidine