瑞舒伐他中间体Z-8结构式
|
常用名 | 瑞舒伐他中间体Z-8 | 英文名 | N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide |
---|---|---|---|---|
CAS号 | 799842-07-2 | 分子量 | 416.308 | |
密度 | 1.5±0.1 g/cm3 | 沸点 | 531.2±60.0 °C at 760 mmHg | |
分子式 | C16H19BrFN3O2S | 熔点 | N/A | |
MSDS | N/A | 闪点 | 275.0±32.9 °C |
中文名 | 5-(溴甲基)-4-(4-氟苯基)-6-异丙基-2-[甲基(甲磺酰)氨基]嘧啶 |
---|---|
英文名 | N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidine-2-yl]-N-methylmethane sulfonamide |
中文别名 | 4-(4-氟苯基)-5-溴甲基-6-异丙基-2-[(N-甲基-N-甲磺酰胺基)]-嘧啶 | N-[4-(4-氟苯基)-5-溴甲基-6-异丙基-2-嘧啶基]-N-甲基甲磺酰胺 | 瑞舒伐他中间体Z-8 | 瑞舒伐他汀钙中间体 |
英文别名 | 更多 |
密度 | 1.5±0.1 g/cm3 |
---|---|
沸点 | 531.2±60.0 °C at 760 mmHg |
分子式 | C16H19BrFN3O2S |
分子量 | 416.308 |
闪点 | 275.0±32.9 °C |
精确质量 | 415.036530 |
PSA | 71.54000 |
LogP | 2.61 |
蒸汽压 | 0.0±1.4 mmHg at 25°C |
折射率 | 1.586 |
储存条件 | 2-8°C,保存于惰性气体中 |
~96% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:YUHAN CORPORATION; JU, Hyun; JOUNG, Sang-Sun; YI, Hyun-Jik; KHOO, Ja-Heouk; LIM, Jong-Chul; KIM, Jae-Gyu Patent: WO2012/2741 A2, 2012 ; Location in patent: Page/Page column 19 ; WO 2012/002741 A2 |
~10% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:Kaneka Corporation Patent: EP2351762 A1, 2011 ; Location in patent: Page/Page column 9 ; |
~90% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ; Location in patent: Page/Page column 57-58 ; |
~% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:WO2012/13325 A1, ; |
~% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:WO2012/13325 A1, ; |
~% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:WO2012/13325 A1, ; |
~% 瑞舒伐他中间体Z-8 799842-07-2 |
文献:WO2012/2741 A2, ; WO 2012/002741 A2 |
瑞舒伐他中间体Z-8上游产品 5 | |
---|---|
瑞舒伐他中间体Z-8下游产品 6 | |
N-[5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide |
Methanesulfonamide, N-[5-(bromomethyl)-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl- |
N-[5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide |
N-[5-(bromomethyl)-4-(4-fluorophenyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide |
N-[5-(bromomethyl)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide |
5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine |
5-(BROMOMETHYL)-4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(METHYL(MET HYLSULFONYL)AMINO)PYRIMIDINE |
N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide |