米法莫肽

更新时间：2024-01-04 13:41:42

米法莫肽结构式	常用名	米法莫肽	英文名	Mifamurtide
	CAS号	83461-56-7	分子量	1237.499
	密度	1.2±0.1 g/cm3	沸点	N/A
	分子式	C₅₉H₁₀₉N₆O₁₉P	熔点	N/A
	MSDS	中文版美版	闪点	N/A

米法莫肽用途

Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。

中文名	米伐木肽
英文名	mifamurtide
中文别名	米法莫肽
英文别名	更多

描述	Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。
相关类别	信号通路 >> 跨膜转运 >> TRP频道研究领域 >> 癌症
参考文献	[1]. Frampton, J.E., Mifamurtide: a review of its use in the treatment of osteosarcoma. Paediatr Drugs, 2010. 12(3): p. 141-53. [2]. Mifamurtide: CGP 19835, CGP 19835A, L-MTP-PE, liposomal MTP-PE, MLV 19835A, MTP-PE, muramyltripeptide phosphatidylethanolamine. Drugs R D, 2008. 9(2): p. 131-5.

描述

Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。

相关类别

信号通路 >> 跨膜转运 >> TRP频道

研究领域 >> 癌症

参考文献

[1]. Frampton, J.E., Mifamurtide: a review of its use in the treatment of osteosarcoma. Paediatr Drugs, 2010. 12(3): p. 141-53.

[2]. Mifamurtide: CGP 19835, CGP 19835A, L-MTP-PE, liposomal MTP-PE, MLV 19835A, MTP-PE, muramyltripeptide phosphatidylethanolamine. Drugs R D, 2008. 9(2): p. 131-5.

密度	1.2±0.1 g/cm3
分子式	C₅₉H₁₀₉N₆O₁₉P
分子量	1237.499
精确质量	1236.748535
PSA	385.91000
LogP	10.98
折射率	1.530
储存条件	2-8℃

Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma.

Expert Rev. Anticancer Ther. 9(8) , 1035-49, (2009)

Osteosarcoma is an ultraorphan disease. There are approximately 1000 new patients diagnosed with osteosarcoma each year in the USA and Europe. Current treatment for osteosarcoma utilizes multiagent ch...

Imunomodulative effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) on mice with alveolar echinococcosis and treated with albendazole.

Parasitol. Res. 103(4) , 919-29, (2008)

The effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) administered separately or with anthelmintic albendazole (ABZ) on cellular immunity of mice with alveolar echinococcosis...

In vitro and in vivo enhancement of canine pulmonary alveolar macrophage cytotoxic activity against canine osteosarcoma cells.

Cancer Biother. Radiopharm. 14(2) , 121-8, (1999)

The combination of chemotherapy with immunotherapy may offer an advantage over either therapy alone and provide a greater potential for total tumor eradication. Monocyte/macrophage-mediated tumor cell...

Mifamurtide

muramyl tripeptide phosphatidylethanolamine

(2R,5S,8R,13S,22R)-2-{[(3R,4R,5S,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}-8-carbamoyl-19-hydroxy-5,13-dimethyl-19-oxido-3,6,11,14,25-pentaoxo-18,20,24-trioxa-4,7,12 ;,15-tetraaza-19λ-phosphatetracontan-22-yl hexadecanoate

N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine