核糖核酸酶H
核糖核酸酶H结构式
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常用名 | 核糖核酸酶H | 英文名 | Ribonuclease H, from Escherichia coli |
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| CAS号 | 9050-76-4 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
核糖核酸酶H用途来自大肠杆菌的核糖核酸酶H已被用于评估镁离子的金属生物化学。 核糖核酸酶H还被用于研究HIV-1逆转录酶相关Rnase H活性的选择性抑制剂。 |
| 中文名 | 核糖核酸酶H |
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| 英文名 | RIBONUCLEASE H |
| 英文别名 | 更多 |
| 描述 | 核糖核酸酶H是一种降解DNA-RNA杂交体RNA部分的酶[1]。 |
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| 参考文献 |
| 外观性状 | 液体 |
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| 储存条件 | −20°C |
| 危险品运输编码 | NONH for all modes of transport |
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| WGK德国 | 1 |
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Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors.
Clin. Infect. Dis. 55(5) , 737-45, (2012) It is not known how often mutations in the connection and ribonuclease H domains of reverse transcriptase (RT) emerge with failure of first-line antiretroviral therapy (ART) in subtype C human immunod... |
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Metallobiochemistry of the magnesium ion. Characterization of the essential metal-binding site in Escherichia coli ribonuclease H.
Eur. J. Biochem. 219 , 253-60, (1994) Ribonuclease H (Escherichia coli) contains one strong magnesium-binding site, as determined by metal-titration experiments monitored by high field 1H-NMR and also by direct titration calorimetry. Kine... |
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Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity
Bioorg. Med. Chem. Lett. 22(12) , 3988-92, (2012) We report herein the synthesis of a series of 3-hydroxyquinolin-2(1H)-one derivatives. Esters and amide groups were introduced at position 4 of the basis scaffold and some modulations of the benzenic ... |
| MFCD00132186 |
