Pantothenate kinase-IN-1

Modify Date: 2024-01-20 13:08:43

Pantothenate kinase-IN-1 structure	Common Name	Pantothenate kinase-IN-1
	CAS Number	1024168-48-6	Molecular Weight	363.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₅N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pantothenate kinase-IN-1

Pantothenate kinase-IN-1 (Compound 1) is a pantothenate kinase (PANK) modulator with an IC50 of 0.51 µM against PANK3. Pantothenate kinase-IN-1 has a reasonable ligand efficiency (LipE = 2.8)[1].

Name	Pantothenate kinase-IN-1

Description	Pantothenate kinase-IN-1 (Compound 1) is a pantothenate kinase (PANK) modulator with an IC50 of 0.51 µM against PANK3. Pantothenate kinase-IN-1 has a reasonable ligand efficiency (LipE = 2.8)[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	IC50: 0.51 µM (PANK3)[1]
References	[1]. Sharma LK, et al. LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg Med Chem. 2021 Dec 15;52:116504.

Molecular Formula	C₂₁H₂₅N₅O
Molecular Weight	363.46