Ro 22-9194

Modify Date: 2024-02-18 09:32:57

Ro 22-9194 structure	Common Name	Ro 22-9194
	CAS Number	106134-33-2	Molecular Weight	384.34300
	Density	N/A	Boiling Point	494.1ºC at 760mmHg
	Molecular Formula	C₁₉H₂₇Cl₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	252.6ºC

Use of Ro 22-9194

Ro 22-9194 inhibits aggregation and thromboxane Az (TXA2) synthetase activity in rabbit and human platelets. Ro 22-9194 has a potent inhibitory action against various types of model arrhythmias. Ro 22-9194 has non-cholinergic cardiac depressant properties with its vasodilating action[1][2].

Name	2-amino-N-(2,6-dimethylphenyl)-N-(3-pyridin-3-ylpropyl)propanamide,dihydrochloride
Synonym	More Synonyms

Description	Ro 22-9194 inhibits aggregation and thromboxane Az (TXA2) synthetase activity in rabbit and human platelets. Ro 22-9194 has a potent inhibitory action against various types of model arrhythmias. Ro 22-9194 has non-cholinergic cardiac depressant properties with its vasodilating action[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. M Murakami, et al. Cardiovascular effects of 2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide dihydrochloride (Ro 22-9194) in the isolated, cross-perfused atrium of the dog. Jpn Heart J. 1990 Sep;31(5):731-9. [2]. I Kodama, et al. Electropharmacology of Ro 22-9194, a new antiarrhythmic agent. Gen Pharmacol. 1996 Jul;27(5):755-60.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

References

[1]. M Murakami, et al. Cardiovascular effects of 2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide dihydrochloride (Ro 22-9194) in the isolated, cross-perfused atrium of the dog. Jpn Heart J. 1990 Sep;31(5):731-9.

[2]. I Kodama, et al. Electropharmacology of Ro 22-9194, a new antiarrhythmic agent. Gen Pharmacol. 1996 Jul;27(5):755-60.

Boiling Point	494.1ºC at 760mmHg
Molecular Formula	C₁₉H₂₇Cl₂N₃O
Molecular Weight	384.34300
Flash Point	252.6ºC
Exact Mass	383.15300
PSA	59.22000
LogP	5.31570
Vapour Pressure	6.62E-10mmHg at 25°C

Ro 22-9194

Ro 22-9194

Use of Ro 22-9194

Names

Ro 22-9194 Biological Activity

Chemical & Physical Properties

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