FD-1080 free acid

Modify Date: 2024-09-07 11:56:22

FD-1080 free acid Structure
FD-1080 free acid structure
Common Name FD-1080 free acid
CAS Number 1151888-25-3 Molecular Weight 743.33
Density N/A Boiling Point N/A
Molecular Formula C40H39ClN2O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FD-1080 free acid


FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].

 Names

Name FD-1080 free acid

 FD-1080 free acid Biological Activity

Description FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].
Related Catalog
In Vitro FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, and can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080-FBS complexes[1].
In Vivo The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth and superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue and high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, and brain vessels was realized, allowing penetration through intact skin, tissue, and skull. FD-1080 also quantifying the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake and anaesthetized mouse[1].
References

[1]. Benhao Li, et al. An Efficient 1064 nm NIR-II Excitation Fluorescent Molecular Dye for Deep-Tissue High-Resolution Dynamic Bioimaging. Angew Chem Int Ed Engl. 2018 Jun 18;57(25):7483-7487.  

 Chemical & Physical Properties

Molecular Formula C40H39ClN2O6S2
Molecular Weight 743.33