3-(Cyclohexylamino)-1-propanesulfonic Acid-d17

Modify Date: 2024-01-08 09:30:18

3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 Structure
3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 structure
Common Name 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17
CAS Number 1219804-15-5 Molecular Weight 238.422
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H2D17NO3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17


3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].

 Names

Name 3-(CyclohexylaMino)-1-propanesulfonic-d17 Acid
Synonym More Synonyms

  Biological Activity

Description 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Bedard P R, et al. Ion Interaction: The Energetics and Mechanism of The Competitive Behavior Between Two Similarly Charged Molecules. 1. The Effect of Ionic Strength, Acetonitrile and Surfactant Concentration[J]. Journal of Liquid Chromatography, 1985, 8(13):2417-2443.

[3]. Oberley TD, et al. The effect of the dimeric and multimeric forms of fibronectin on the adhesion and growth of primary glomerular cells. Exp Cell Res. 1983 May145(2):265-76.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C9H2D17NO3S
Molecular Weight 238.422
Exact Mass 238.215271
LogP 0.05
Index of Refraction 1.515

 Synonyms

3-[(2H11)Cyclohexylamino]-1-(2H6)propanesulfonic acid
1-Propane-1,1,2,2,3,3-d6-sulfonic acid, 3-(cyclohexyl-d11-amino)-
3-[(2H11)Cyclohexylamino](2H6)propane-1-sulfonic acid