Itopride-d6 hydrochloride

Modify Date: 2024-01-12 23:14:43

Itopride-d6 hydrochloride structure	Common Name	Itopride-d6 hydrochloride
	CAS Number	1346601-02-2	Molecular Weight	400.93
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₁D₆ClN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Itopride-d6 hydrochloride

Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].

Name	Itopride-d6 hydrochloride

Description	Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. [3]. Kenjiro Matsumoto, et al. Validation of 13 C-Acetic Acid Breath Test by Measuring Effects of Loperamide, Morphine, Mosapride, and Itopride on Gastric Emptying in Mice. Biol Pharm Bull. 2008 Oct;31(10):1917-22.

Molecular Formula	C₂₀H₂₁D₆ClN₂O₄
Molecular Weight	400.93

Itopride-d6 hydrochloride

Use of Itopride-d6 hydrochloride

Names

Itopride-d6 hydrochloride Biological Activity

Chemical & Physical Properties