S-14671

Modify Date: 2023-01-18 23:25:27

S-14671 Structure
S-14671 structure
Common Name S-14671
CAS Number 135722-27-9 Molecular Weight 395.51800
Density 1.225g/cm3 Boiling Point 646.7ºC at 760 mmHg
Molecular Formula C22H25N3O2S Melting Point N/A
MSDS N/A Flash Point 344.9ºC

 Use of S-14671


S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3). S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].

 Names

Name N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]thiophene-2-carboxamide
Synonym More Synonyms

 S-14671 Biological Activity

Description S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3). S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].
Related Catalog
Target

5-HT1A Receptor:9.3 (pKi)

References

[1]. Millan MJ, et al. S 14671: a novel naphthylpiperazine 5-HT1A agonist of high efficacy and exceptional in vivo potency. Eur J Pharmacol. 1991 Oct 15;203(2):319-22.  

 Chemical & Physical Properties

Density 1.225g/cm3
Boiling Point 646.7ºC at 760 mmHg
Molecular Formula C22H25N3O2S
Molecular Weight 395.51800
Flash Point 344.9ºC
Exact Mass 395.16700
PSA 73.05000
LogP 3.85570
Vapour Pressure 1.3E-16mmHg at 25°C
Index of Refraction 1.634

 Synonyms

4-((Thenoyl)-2-aminoethyl)-1-(7-methoxynaphthylpiperazine)
N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}thiophene-2-carboxamide
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