N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C

Modify Date: 2024-01-10 00:09:31

N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C Structure
N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C structure
Common Name N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C
CAS Number 202114-53-2 Molecular Weight 354.40
Density 1.2±0.1 g/cm3 Boiling Point 559.8±33.0 °C at 760 mmHg
Molecular Formula C2013CH23NO4 Melting Point 152-156ºC(lit.)
MSDS Chinese USA Flash Point 292.4±25.4 °C

 Use of N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C


Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].

 Names

Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Synonym More Synonyms

  Biological Activity

Description Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 559.8±33.0 °C at 760 mmHg
Melting Point 152-156ºC(lit.)
Molecular Formula C2013CH23NO4
Molecular Weight 354.40
Flash Point 292.4±25.4 °C
Exact Mass 353.162720
PSA 75.63000
LogP 4.95
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.583

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

L-Leucine-1-13C,N-Fmoc
N-(9-Fluorenylmethoxycarbonyl)-L-leucine-1-13C,L-Leucine-1-13C,N-Fmoc
MFCD00190328
Fmoc-D-Leu-OH
Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-Leu-OH-1-13C
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]leucine