JTP-117968

Modify Date: 2024-01-14 09:36:18

JTP-117968 structure	Common Name	JTP-117968
	CAS Number	2250132-99-9	Molecular Weight	520.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₁F₃N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JTP-117968

JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].

Name	JTP-117968

Description	JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
In Vitro	JTP-117968 has partial TR activity, but exhibits extremely low TA activity[1].
References	[1]. Takafumi Kurimoto, et al. JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation. Eur J Pharmacol. 2017 May 15;803:179-186.

Molecular Formula	C₃₁H₃₁F₃N₂O₂
Molecular Weight	520.59