IONIS-FB-LRx

Modify Date: 2024-01-17 08:29:14

IONIS-FB-LRx structure	Common Name	IONIS-FB-LRx
	CAS Number	2272975-74-1	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	N/A	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IONIS-FB-LRx

IONIS-FB-LRx is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx effectively reduces circulating levels of CFB. IONIS-FB-LRx can be used for geographic atrophy (GA) research[1][2].

Name	IONIS-FB-LRx

Description	IONIS-FB-LRx is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx effectively reduces circulating levels of CFB. IONIS-FB-LRx can be used for geographic atrophy (GA) research[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Immunology/Inflammation >> Complement System
Target	Complement factor B (CFB)[1]
In Vivo	IONIS-FB-Lrx is administered by subcutaneous injection every four weeks and targets CFB’s hepatic expression[2].
References	[1]. Dreismann AK, et al. Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway. Immunol Rev. 2022 Nov 12. [2]. Mahmoudzadeh R, et al. Emerging treatments for geographic atrophy in age-related macular degeneration. Curr Opin Ophthalmol. 2021 May 1;32(3):294-300.

No Any Chemical & Physical Properties

IONIS-FB-LRx

Use of IONIS-FB-LRx

Names

IONIS-FB-LRx Biological Activity

Chemical & Physical Properties