Melatonin receptor agonist 1

Modify Date: 2024-01-13 06:58:09

Melatonin receptor agonist 1 Structure
Melatonin receptor agonist 1 structure
Common Name Melatonin receptor agonist 1
CAS Number 2411150-76-8 Molecular Weight 273.33
Density N/A Boiling Point N/A
Molecular Formula C15H19N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Melatonin receptor agonist 1


Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].

 Names

Name Melatonin receptor agonist 1

 Melatonin receptor agonist 1 Biological Activity

Description Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1].
Related Catalog
Target

MT2:108 nM (Ki)

MT1:1140 nM (Ki)

In Vitro Melatonin receptor agonist 1 (compound 20c) shows a 10 times MT2-selectivity over MT1[1].
References

[1]. Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078.

 Chemical & Physical Properties

Molecular Formula C15H19N3O2
Molecular Weight 273.33