Tamsulosin-d4 hydrochloride

Modify Date: 2024-01-16 18:42:57

Tamsulosin-d4 hydrochloride Structure
Tamsulosin-d4 hydrochloride structure
Common Name Tamsulosin-d4 hydrochloride
CAS Number 2518100-55-3 Molecular Weight 449.00
Density N/A Boiling Point N/A
Molecular Formula C20H25D4ClN2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tamsulosin-d4 hydrochloride


Tamsulosin-d4 (hydrochloride) is deuterium labeled Tamsulosin (hydrochloride). Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models[1].

 Names

Name Tamsulosin-d4 hydrochloride

 Tamsulosin-d4 hydrochloride Biological Activity

Description Tamsulosin-d4 (hydrochloride) is deuterium labeled Tamsulosin (hydrochloride). Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Christopher Chapple, et al. Tamsulosin: an overview. World J Urol. 2002 Apr;19(6):397-404.

[3]. William G. Montgomery, BA, et al. Tamsulosin Attenuates Abdominal Aortic Aneurysm Growth. Surgery. 2018 Nov; 164(5): 1087-1092.

 Chemical & Physical Properties

Molecular Formula C20H25D4ClN2O5S
Molecular Weight 449.00