IDO1-IN-16

Modify Date: 2024-01-08 16:06:40

Use of IDO1-IN-16

IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC50 of 127 nM[1].

Name	IDO1-IN-16

Description	IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC50 of 127 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
Target	IDO1:127 nM (IC50)
References	[1]. Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373.

Molecular Formula	C₂₅H₃₅BrFN₅O₂
Molecular Weight	536.48