Moxifloxacin-d3 hydrochloride

Modify Date: 2024-01-23 22:18:12

Moxifloxacin-d3 hydrochloride Structure
Moxifloxacin-d3 hydrochloride structure
Common Name Moxifloxacin-d3 hydrochloride
CAS Number 2734919-98-1 Molecular Weight 440.91
Density N/A Boiling Point N/A
Molecular Formula C21H22D3ClFN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Moxifloxacin-d3 hydrochloride


Moxifloxacin-d3 hydrochloride is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin hydrochloride is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2][3].

 Names

Name Moxifloxacin-d3 hydrochloride

 Moxifloxacin-d3 hydrochloride Biological Activity

Description Moxifloxacin-d3 hydrochloride is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin hydrochloride is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Culley, C.M., et al., Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm, 2001. 58(5): p. 379-88.  

[3]. Grayo S, et al. Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. Antimicrob Agents Chemother. 2008 May;52(5):1697-702.  

 Chemical & Physical Properties

Molecular Formula C21H22D3ClFN3O4
Molecular Weight 440.91