p-Hydroxybenzaldehyde-d5

Modify Date: 2024-01-11 07:47:32

p-Hydroxybenzaldehyde-d5 Structure
p-Hydroxybenzaldehyde-d5 structure
Common Name p-Hydroxybenzaldehyde-d5
CAS Number 298704-22-0 Molecular Weight 127.15200
Density N/A Boiling Point N/A
Molecular Formula C7HD5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of p-Hydroxybenzaldehyde-d5


p-Hydroxybenzaldehyde-d5 is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].

 Names

Name 4-hydroxy-[2,3,5,6,7-2H5]-benzaldehyde
Synonym More Synonyms

 p-Hydroxybenzaldehyde-d5 Biological Activity

Description p-Hydroxybenzaldehyde-d5 is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Zhang J, et al. The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor. Malays J Med Sci. 2017 Mar;24(2):94-99.  

 Chemical & Physical Properties

Molecular Formula C7HD5O2
Molecular Weight 127.15200
Exact Mass 127.06800
PSA 37.30000
LogP 1.20470

 Synonyms

4-hydroxy-2,3,5,6-d4-benz(aldehyde-d1)
4-Hydroxybenzaldehyde-Alpha,2,3,5,6-d5
2,3,5,6-d4-4-hydroxy-benzaldehyde-d1