Antiviral agent 23

Modify Date: 2024-04-05 18:31:48

Antiviral agent 23 Structure
Antiviral agent 23 structure
Common Name Antiviral agent 23
CAS Number 35940-03-5 Molecular Weight 371.39
Density N/A Boiling Point N/A
Molecular Formula C18H21N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiviral agent 23


Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1].

 Names

Name Antiviral agent 23

 Antiviral agent 23 Biological Activity

Description Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1].
Related Catalog
In Vitro Antiviral agent 23 (0-100 μM) 抑制 CVA21 和 EV68 在 HeLa 细胞中的复制,其 EC50 值分别为 36.4 和 8.9 μM[1]。 Antiviral agent 23 (100 μM) 抑制 METTL3/METTL14 的酶活,至 74.45%[1]。 Antiviral agent 23 (0-100 μM) 抑制 EV71 毒株 BrCr 在 RD 细胞中的复制,EC50 值为 94 nM[1]。
References

[1]. Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942.  

 Chemical & Physical Properties

Molecular Formula C18H21N5O4
Molecular Weight 371.39